The Fourth Edition of this textbook teaches the artful science of the patient interview and the physical examination - from the fundamentals to the most advanced levels. Written in an artful storytelling style, the book describes methods in step-by-step detail, with clinical pearls, vignettes, practical clinical experience, personal history, explanations of the physiologic significance of findings, and extensive discussions of evidence-based medicine. Even with all of today's sophisticated laboratory and imaging technology, a skillfully performed patient interview and physical examination can be a quicker and more cost-effective route to an accurate diagnosis. The Fourth Edition of "Sapira's Art and Science of Bedside Diagnosis" is your guide to gaining the most reliable information from your patients, developing a differential diagnosis and an efficient diagnostic strategy.