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Table of Contents
1. Genetics: An Introduction.
I. GENES AND THEIR FUNCTIONS.
2. DNA-The Genetic Material.
3. DNA Replication.
4. Gene Control of Proteins.
5. Gene Expression-Transcription.
6. Gene Expression-Translation.
II. GENE MANIPULATION AND GENOMIC ANALYSIS.
7. DNA Cloning and Manipulation.
8. Applications of Recombinant DNA Technology.
9. Genome Analysis.
III. PRINCIPLES OF GENE SEGREGATION ANALYSIS.
10. Mendelian Genetics.
11. Chromosomal Basis of Inheritance, Sex Linkage, and Sex Determination.
12. Extensions of Mendelian Genetic Analysis.
13. Gene Mapping in Eukaryotes.
14. Gene Mapping in Bacteria and Bacteriophages.
15. Non-Mendelian Inheritance.
IV. REGULATION OF GENE EXPRESSION.
16. Regulation of Gene Expression in Bacteria and Bacteriophages.
17. Regulation of Gene Expression in Eukaryotes.
18. Genetics of Cancer.
V. GENETIC CHANGE.
19. DNA Mutation and Repair.
20. Transposable Elements.
21. Chromosomal Mutations.
VI. GENETICS OF POPULATIONS.
22. Population Genetics.
23. Quantitative Genetics.
24. Molecular Evolution.
Features Cutting edge chapters on Genome Analysis and Molecular Evolution. iGenetics CD-ROM free with every new text, includes 50 animations, 24 iActivities, and hundreds of interactive problem-solving exercises that help students grasp abstract processes and active problem solving. This free student CD-ROM is available in two versions one with solutions for all the problems in the text and one without. 24 iActivities one for each text chapter promote interactive problem solving. Building on chapter-opening case studies, the iActivities present real-life genetics problems that help develop students' critical thinking skills and actively engage them in applying their understanding of genetics. Media flags throughout the text direct students to 50 narrated animations on the iGenetics CD-ROM; these animations (all scripted and developed by Peter Russell) help students visualize challenging concepts. For example, animations of meiosis and recombinant DNA bring text images to life by taking students through a process from start to finish, thereby reinforcing the content. Step-by-step problem sets throughout the book represent a wide range of topics and difficulty levels, and give students practice in problem solving. Experimental data emphasizes an inquiry-based approach and engages students in the process of science. Pedagogy:
Principal Points, appearing at the beginning of each chapter, alert students to key concepts.
Keynotes, at the end of each new topic within a chapter, summarize important ideas and allow students to check their progress.
Summary at the end of each chapter ties all the main points together.
Analytical Approaches at the end of each chapter guide students step-by-step through genetic problems. Human examples help students comprehend new molecular understandings of various human genetic diseases.
Peter J. Russell received his B.Sc. in Biology from University of Sussex in 1968 and his Ph.D. in Genetics from Cornell University in 1972. He then joined the Biology faculty of Reed College in 1972 where he is currently Professor of Biology. Russell teaches an upper-division genetics and molecular biology lecture/laboratory course, the genetics section of the introductory biology course, an advanced seminar course in yeast virology, and advises senior thesis research students. He is also the author of a number of successful genetics textbooks.
He is currently studying the molecular genetics of the replication of double-stranded (ds)RNA viruses found in budding yeast, Saccharomyces cerevisiae. The research goals are to define in vivo the cis-acting sequences that are required for viral RNA packaging into capsids and for genome replication, and to identify and characterize any yeast gene products required for virus propagation. His earlier research involved Neurospora rRNA synthesis and the organization of and regulation of the number of ribosomal RNA genes, and nitrogen metabolism in the pathogenic dimorphic yeast Candida albicans.
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