"This volume is a very valuable and much needed
contribution." –Quarterly Review of Biology AT LAST – A
comprehensive, accessible textbook on glial
neurobiology! Glial cells are the most numerous cells in
the human brain but for many years have attracted little
scientific attention. Neurophysiologists concentrated
their research efforts instead, on neurones and neuronal
networks because it was thought that they were the key
elements responsible for higher brain function. Recent
advances, however, indicate this isn’t exactly the case.
Not only are astroglial cells the stem elements from
which neurones are born, but they also control the
development, functional activity and death of neuronal
circuits. These ground–breaking developments have
revolutionized our understanding of the human brain and
the complex interrelationship of glial and neuronal
networks in health and disease. Features of this book:
an accessible introduction to glial neurobiology
including an overview of glial cell function and its
active role in neural processes, brain function and
nervous system pathology an exploration of all the major
types of glial cells including: the astrocytes,
oligodendrocytes and microglia of the ACNS and Schwann
cells of the peripheral nervous system; the book also
presents a broad overview of glial receptors and ion
channels an investigation into the role of glial cells
in various types of brain diseases including stroke,
neurodegenerative diseases such as Alzheimer′s,
Parkinson′s and Alexander′s disease, brain oedema,
multiple sclerosis and many more a wealth of
illustrations, including unique images from the authors′
own libraries of images, describing the main features of
glial cells Written by two leading experts in the field,
Glial Neurobiology provides a concise, authoritative
introduction to glial physiology and pathology for
undergraduate/postgraduate neuroscience, biomedical,
medical, pharmacy, pharmacology, and neurology,
neurosurgery and physiology students. It is also an
invaluable resource for researchers in
neuroscience, physiology, pharmacology and
pharmaceutics.
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