1. Pickart, L. A tripepeptide in human serum that promotes the growth of hepatoma cells and the survival of normal hepatocytes, Ph.D. thesis, Univ. of California, San Francisco, 1973
2. Pickart, L. , Copper Peptides for Tissue Regeneration, Speciality Chemicals 2002 (October) pages 29-31
3. Pickart, L., Reversing Skin Aging with Copper Peptides, Body Language Dermatol. 2003 (April) pages 12-13
4. Pickart, L., Copperceuticals and the Skin, Cosmetics & Toiletries 2003; 118, 24-28.
5. Ellis, J.A., Stebbing, M., Harrap, S.B., Genetic analysis of male pattern baldness and the 5-alpha reductase genes, J Invest Dermatol 1998; 110, 849-853
6. Uno, H., The Histopathology of Hair Loss (Publisher: The UpJohn Company, Kalamazoo, MI) 1988
7. The Molecular and Structural Biology of Hair (Stenn K.S., Messenger A.G., and Baden H.P, (eds). Ann NY Acad Sci; New York: New York Academy of Sciences) 1991.
8. Jahoda, C.A., Whitehouse, J., Reynolds, A.J., Hole, N., Hair follicle dermal cells differentiate into adipogenic and osteogenic lineages. Exp Dermatol. 2003; 12, 849-859.
9. Lavker, R.M., Sun, T.T., Oshima, H., Barrandon, Y., Akiyama ,M., Ferraris, C., Chevalier, G., Favier, B., Jahoda, C.A., Dhouailly, D., Panteleyev, A.A., Christiano, A.M., Hair follicle stem cells, J Investig Dermatol, 2003; 8, 28-38
10. Pickart, L., New metal peptide complexes and derivatives used for stimulating growth of hair in warm-blooded animals, especially humans, US Patent 5,120,831; Compositions for stimulating hair growth containing cupric complexes of peptide derivatives including. glycyl-l- histidyl-l-lysine n-octyl ester. US Patent 5,177,061; New glycyl-histidyl-lysyl copper compounds used in stimulating hair growth; US Patent 5,214,032; Metal-peptide compositions and methods for stimulating hair growth, US Patent 5,550,183
11. Trachy, R., Fors, T.D., Pickart, L. Uno, H. The hair follicle stimulating properties of peptide copper complexes. Results in C3H mice. Ann N Y Acad Sci 1991;642, 468-469
12. Uno, H., Kurata, S. Chemical agents and peptides affect hair growth. J. Invest Dermatol 1993; 101, 143S-147S
13. Awa, T., Nogimori, K., Trachy, R. Hairloss protection by peptide-copper complex in animal models of chemotherapy-induced alopecia. J Dermatol Sci 1995; 10, 99-104
14. Trachy, R., Patt, L., Duncan, G., Kalis, B., Phototrichogram Analysis of Hair Follicle Stimulation: A pilot clinical study with a peptide-copper complex, in: Dermatological Research Techniques, (Edited by H.I. Maibach, CRC Press), 1996, pp-217-226
15. Press release, Procyte Corporation, 1997
16. Perez-Meza, D., Leavitt, M., Trachy, R. Clinical evaluation of GraftCyte Moist Dressing on hair graft viability and quality of healing. Inter J Cos Surg 1998; 6, 80-84
17. Hitzig,G. Enhanced healing and growth in hair transplantation using copper peptides, Cosmetic Dermatol 2000 (June) ; 13, 18-21
18. Hitzig,G. Enhanced healing and growth in hair transplantation using copper peptides, Cosmetic Dermatol 2000 (June) ; 13, 18-21
19. Pickart, L., New glycyl-histidyl-lysine ester copper complex compounds with anti-inflammatory and superoxide dismutase activity useful for enhancing wound healing. US Patent 4,877,770; New anti-oxidative and anti-inflammatory metal peptide complexes - containing. glycyl histidyl and lysine residues used to enhance or restore resistance to oxidative or inflammatory damage. US 5,118,665
20. Vinci C., Caltabiano V., Santoro A.M., Rabuazzo A.M., Buscema M., Purrello R., Rizzarelli E. Copper addition prevents the inhibitory effects of interleukin 1-beta on rat pancreatic islets. Diabetologia. 1995; 38:39-45
21. McCormack MC, Nowak KC, Koch RJ. The effect of copper tripeptide and tretinoin on growth factor production in a serum-free fibroblast model. Arch Facial Plast Surg 2001; 3:28-32
22. Miller D.M., DeSilva D., Pickart L., Aust S.D. Effects of glycyl-histidyl-lysyl chelated Cu(II) on ferritin dependent lipid peroxidation. Adv Exp Med Biol 1990; 264: 79-84
23. Zhai H., Chang Y.C., Singh M., Maibach H.J. In vivo nickel contact dermatitis: human model for topical therapeutics. Contact Dermatitis 1999; 40: 205-208
24. Pickart, L., Skin treatment composition comprises GHL-CU or derivatives for improving skin health, increasing subcutaneous fat, dermal thickness and density. US Patent 5,135,913
25. Pickart, L., Tissue protective and regenerative compositions, US Patents 5,382,431, US 5,888,522, US 5,554,375
Note on reference 25 – The title of all three patents is the same. But they make different claims on the same text.
26. Zhai H., Poblete N., Maibach H.J. Stripped skin model to predict irritation potential of topical agents in vivo in man. Inter J Dermatol 1998; 37: 386-389
27. Zhai H., Leow Y.H., Maibach H.R., Human barrier recovery after acute acetone perturbation: an irritant dermatitis model. Clin Exp Derm, 1998: 23: 11-13
28. Zhai H., Leow Y.H., Maibach H.R., Sodium lauryl sulfate damaged skin in vivo in man: a water barrier repair model. Skin Res Tech, 1998: 4: 24-27
29. For more references, see www.skinbiology.com/copperpeptideregeneration.html