Just as Megamind has become our new Mega Hero, a sudden crime wave hits the city. The Doom Syndicate & their Doom Goons have emerged and are looking to take over! Only Megamind and his arsenal of gadgets can stop them

In Megamind: Ultimate Showdown the story begins after the movie ends with Megamind being the new hero of Metro City. A sudden crime wave hits the city, orchestrated by an organization called the Doom Syndicate. The Doom Syndicate have broken into Megamind's secret lair and obtained samples of Megamind's and Metro Man's DNA along with Megamind's DNA tracking device. It's up to Megamind to hunt down the Doom Syndicate, stop the crime wave and find the missing pieces of the DNA Tracker to locate and battle against Blue Tighten.

In Megamind: Mega Team Unite, Tighten is a good guy (assuming he has seen the error of his ways since the movie story) and joins Megamind, Minion and Metro Man to battle against the Doom Syndicate. They battle Destruction Worker and track down other Doom Syndicate members to defeat them as well. Their adventure is broadcast "live on the scene" by Roxanne Richie, who follows them and gives them helpful hints.

• Become the On-The-Go Mega Hero - Play as Megamind, anytime, anywhere
• Defend the City! - Find and defeat new Doom Syndicate enemies, including Megamind's re-programmed Brainbots!
• Collect & Upgrade a Blaster Arsenal - Switch between blasters on the fly which become more powerful the more they are used!