Take control of Earth Command Lieutenant, Aileen Harding, as she adventures through intense sci-fi battles against hordes of unique aliens and huge bosses. With an array of special abilities and combat powers, you'll draw on quick reflexes and skill plus a wide choice of weapons, armor, and items to defeat increasingly formidable opponents.

Alien Syndrome on the Wii will utilise the Wii remote's unique gyroscopic feature by enabling players a full range of motion when slashing through enemies, unloading devastation on bosses, or running and gunning through hallways.